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ionoptix-μstep myocyte contractility system  (IonOptix)

 
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    Structured Review

    IonOptix ionoptix-μstep myocyte contractility system
    Tβ4 −/Y mice possess limited contractile reserve. Mid-ventricular short axis images, at baseline and under dobutamine stress, were acquired at high frame rate. Tβ4 +/Y: A–D; Tβ4 −/Y: E–H. End systolic volume at baseline of Tβ4 −/Y mice (F) is considerably reduced compared with control (+/Y) mice (B; Table A4; n = 4 +/Y, 6 −/Y), limiting the extent to which LV <t>contractility</t> can be further increased under dobutamine stress (Tβ4 +/Y: D; Tβ4 −/Y: H). Representative volume curves for +/Y (I) and −/Y mice (J) demonstrate reduced contractile reserve (characteristic leftward shift, as observed in +/Y) in −/Y mice upon β-adrenergic stimulation (shown for n = 2 each genotype).
    Ionoptix μstep Myocyte Contractility System, supplied by IonOptix, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ionoptix-%CE%BCstep+myocyte+contractility+system/pmc05319848-61-12-11?v=IonOptix
    Average 90 stars, based on 1 article reviews
    ionoptix-μstep myocyte contractility system - by Bioz Stars, 2026-08
    90/100 stars

    Images

    1) Product Images from "Aberrant developmental titin splicing and dysregulated sarcomere length in Thymosin β4 knockout mice"

    Article Title: Aberrant developmental titin splicing and dysregulated sarcomere length in Thymosin β4 knockout mice

    Journal: Journal of Molecular and Cellular Cardiology

    doi: 10.1016/j.yjmcc.2016.10.010

    Tβ4 −/Y mice possess limited contractile reserve. Mid-ventricular short axis images, at baseline and under dobutamine stress, were acquired at high frame rate. Tβ4 +/Y: A–D; Tβ4 −/Y: E–H. End systolic volume at baseline of Tβ4 −/Y mice (F) is considerably reduced compared with control (+/Y) mice (B; Table A4; n = 4 +/Y, 6 −/Y), limiting the extent to which LV contractility can be further increased under dobutamine stress (Tβ4 +/Y: D; Tβ4 −/Y: H). Representative volume curves for +/Y (I) and −/Y mice (J) demonstrate reduced contractile reserve (characteristic leftward shift, as observed in +/Y) in −/Y mice upon β-adrenergic stimulation (shown for n = 2 each genotype).
    Figure Legend Snippet: Tβ4 −/Y mice possess limited contractile reserve. Mid-ventricular short axis images, at baseline and under dobutamine stress, were acquired at high frame rate. Tβ4 +/Y: A–D; Tβ4 −/Y: E–H. End systolic volume at baseline of Tβ4 −/Y mice (F) is considerably reduced compared with control (+/Y) mice (B; Table A4; n = 4 +/Y, 6 −/Y), limiting the extent to which LV contractility can be further increased under dobutamine stress (Tβ4 +/Y: D; Tβ4 −/Y: H). Representative volume curves for +/Y (I) and −/Y mice (J) demonstrate reduced contractile reserve (characteristic leftward shift, as observed in +/Y) in −/Y mice upon β-adrenergic stimulation (shown for n = 2 each genotype).

    Techniques Used: Control



    Similar Products

    90
    IonOptix ionoptix-μstep myocyte contractility system
    Tβ4 −/Y mice possess limited contractile reserve. Mid-ventricular short axis images, at baseline and under dobutamine stress, were acquired at high frame rate. Tβ4 +/Y: A–D; Tβ4 −/Y: E–H. End systolic volume at baseline of Tβ4 −/Y mice (F) is considerably reduced compared with control (+/Y) mice (B; Table A4; n = 4 +/Y, 6 −/Y), limiting the extent to which LV <t>contractility</t> can be further increased under dobutamine stress (Tβ4 +/Y: D; Tβ4 −/Y: H). Representative volume curves for +/Y (I) and −/Y mice (J) demonstrate reduced contractile reserve (characteristic leftward shift, as observed in +/Y) in −/Y mice upon β-adrenergic stimulation (shown for n = 2 each genotype).
    Ionoptix μstep Myocyte Contractility System, supplied by IonOptix, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ionoptix-%CE%BCstep+myocyte+contractility+system/pmc05319848-61-12-11?v=IonOptix
    Average 90 stars, based on 1 article reviews
    ionoptix-μstep myocyte contractility system - by Bioz Stars, 2026-08
    90/100 stars
      Buy from Supplier

    Image Search Results


    Tβ4 −/Y mice possess limited contractile reserve. Mid-ventricular short axis images, at baseline and under dobutamine stress, were acquired at high frame rate. Tβ4 +/Y: A–D; Tβ4 −/Y: E–H. End systolic volume at baseline of Tβ4 −/Y mice (F) is considerably reduced compared with control (+/Y) mice (B; Table A4; n = 4 +/Y, 6 −/Y), limiting the extent to which LV contractility can be further increased under dobutamine stress (Tβ4 +/Y: D; Tβ4 −/Y: H). Representative volume curves for +/Y (I) and −/Y mice (J) demonstrate reduced contractile reserve (characteristic leftward shift, as observed in +/Y) in −/Y mice upon β-adrenergic stimulation (shown for n = 2 each genotype).

    Journal: Journal of Molecular and Cellular Cardiology

    Article Title: Aberrant developmental titin splicing and dysregulated sarcomere length in Thymosin β4 knockout mice

    doi: 10.1016/j.yjmcc.2016.10.010

    Figure Lengend Snippet: Tβ4 −/Y mice possess limited contractile reserve. Mid-ventricular short axis images, at baseline and under dobutamine stress, were acquired at high frame rate. Tβ4 +/Y: A–D; Tβ4 −/Y: E–H. End systolic volume at baseline of Tβ4 −/Y mice (F) is considerably reduced compared with control (+/Y) mice (B; Table A4; n = 4 +/Y, 6 −/Y), limiting the extent to which LV contractility can be further increased under dobutamine stress (Tβ4 +/Y: D; Tβ4 −/Y: H). Representative volume curves for +/Y (I) and −/Y mice (J) demonstrate reduced contractile reserve (characteristic leftward shift, as observed in +/Y) in −/Y mice upon β-adrenergic stimulation (shown for n = 2 each genotype).

    Article Snippet: Functional assessment was conducted, within 6 h of isolation, using an IonOptix-μStep Myocyte Contractility System.

    Techniques: Control